Endocrine Abstracts

Introduction: Primary adrenal insufficiency (PAI) is a rare disease with a prevalence of 82–144 cases/milion. The etiology of PAI is represented primarily by autoimmune adrenalitis, followed by tuberculosis and less common by fungal infections, HIV, hemorrage in adrenal glands, certain drugs and by some genetic disorders such as Triple A syndrome (AAA), Adrenoleukodystrophy (ALD), congenital adrenal hypoplasia, congenital adrenal hyperplasia, etc.C...

Introduction: Adrenal carcinomas are rare tumor. It has an estimated incidence of ~0.5–2 new cases per million people per year. Just 25% of adults with hormone-secreting adrenal carcinomas present overproduction of both glucocorticoids and androgens. Women develop adrenal carcinomas more often than men.Objectives: We report a case of 47-year-old female presented with weight gain, generalized weakness and hypertension for the last 6 months. Phy...

Background and Aims: GH receptor antagonist (Pegvisomant –PEG) has been shown to obtain IGF1 normalization in 60–90% of patients with acromegaly in clinical trials. The aim of the study is to evaluate real life response and side effects of PEG treatment in monotherapy versus combined with somatostatin analogues and/or cabergoline in patients with somatostatin analogues resistant acromegaly.Methods: We included 40 patients (22F/18 M) cons...

Graves’ disease is an autoimmune thyroid disease which, untreated, carries a significant morbidity risk. Treatment options for Graves’s disease have changed over the decades.AimsTo evaluate the outcome and risk factors for relapses of patients with Graves’s disease treated with antithyroid drugs for at least 2 years.MethodsA retrospective, analytic study on 360 consecutiv...